For the treatment of nosocomial infections caused , need combination therapy. During treatment oxandrolone side effects should avoid direct sunlight and artificial radiation (solarium), in order to avoid the development of photosensitivity reactions. It should be in mind that patients with brain damage in history (stroke, severe head injury) may develop seizures, with insufficient glucose-6-phosphate dehydrogenase – the risk of hemolytic reaction. since levofloxacin is excreted mainly by the kidneys, patients with impaired renal function requires control of renal function as well as correction of dosing regimen. It was reported about lengthening interval in patients receiving fluoroquinolones, including levofloxacin. When using fluoroquinolones, including levofloxacin, caution should be exercised in patients with known risk factors for prolongation of the interval : uncorrected violation of water-electrolyte imbalance (hypokalemia, hypomagnesemia); congenital syndrome interval; heart disease (heart failure, myocardial infarction, bradycardia); concomitant use of drugs that can prolong interval. Elderly patients and female patients may be more sensitive to the drug, prolongs interval. It should therefore be used with caution in these fluoroquinolones, including tren steroid. In patients with diabetes mellitus who receive oral hypoglycemic agents (e.g. glibenclamide) or insulin, the application of levofloxacin increases the risk of hypo / hyperglycemia. Reported cases of hypoglycemic coma. In patients with diabetes need to monitor blood glucose. In patients receiving fluoroquinolones, including levofloxacin, marked sensory and sensory-motor peripheral neuropathy, the beginning of which can be rapid. When the patient symptoms of neuropathy, the use of tablets oxandrolone side effects should be discontinued (to minimize possible risk of irreversible changes). Should not be used in patients with gravis (myasthenia gravis). When using quinolones, including levofloxacin, reported on the development of psychotic reactions, which in rare cases progressed to the development of suicidal thoughts and behavior disorders with self-harm (sometimes after receiving a single dose of levofloxacin). With the development of these reactions treatment ta should be discontinued and prescribe appropriate therapy. It should be used with caution to patients with psychosis or patients with a history of mental illness. With the development of any impairment requires immediate consultation of the ophthalmologist. Patients with severe community-acquired pneumonia caused by Streptococcus pneumoniae, tablets Fleksid ® can not provide the optimal therapeutic effect. Levofloxacin may inhibit growth Mycobacterium tuberculosis, therefore, possible false-negative results of bacteriological tests for TB. patients oxandrolone side effects , determination of opiates in urine may lead to false positive results, which should be acknowledged more specific methods.