Increase in activity of “liver” enzymes oxandrolone 10mg and alkaline phosphatase. Very rarely there are cases of aseptic meningitis. Rare: malaise, unpleasant taste in the mouth, salivation, conjunctivitis, scotoma, blurred vision, pain in the ear, increased fragility of nails, weight changes, swelling of the glands, nasal congestion;
Overdosing Symptoms: nausea, weakness, dizziness, tachycardia, decreased blood pressure, hyperthermia, drowsiness or agitation, loss of consciousness, areflexia, clonic-tonic convulsions, as a sign of gastrointestinal bleeding, vomiting like “coffee grounds”. Treatment: No specific antidote .
If after administration of the drug was not long, there should be gastric lavage (to prevent further absorption of the drug) and assign the activated carbon. In the case of vomiting with traces of blood gastric lavage is not allowed.
Conduct symptomatic therapy.
Interaction with other drugs
Pentoxifylline potentiates the anticoagulant effect of heparin, fibrinolytic agents, enhances the effect of antihypertensive and hypoglycemic agents (insulin and oral hypoglycemic agents).
Pentoxifylline may increase the effects of antibiotics (including cephalosporins -tsefamandola, tsefotetan), valproic acid.
Pentoxifylline cimetidine increases the concentration in plasma (the risk of side effects).
Co-administration with other xanthines can lead to excessive nervous excitement patients.
Be careful when appointing oxandrolone 10mg patients with severe cerebral and / or coronary atherosclerosis, particularly with concomitant hypertension and cardiac arrhythmias. These patients may be angina, arrhythmias and hypotension.
With care should be prescribed to patients with gastric ulcer and duodenal ulcer (including history); patients who have recently undergone surgery (in these cases there is an increased risk of bleeding, so you need systematic monitoring of hemoglobin concentration and hematocrit).
In the case of the drug in patients with chronic heart failure previously to be achieved phase circulatory compensation. Patients with labile blood pressure, or with a tendency to hypotension dose increased gradually. Patients with severe renal impairment dose picked individually. In the case of simultaneous application Fleksitala and oral anticoagulants requires regular monitoring of the prothrombin time. In an application Fleksitala and antidiabetic or antihypertensive agents last dose of drugs should be reduced.
In case of bleeding in the retina of the eye during treatment necessary to stop the drug immediately.
Drug treatment should be under oxandrolone 10mg the control of blood pressure. dose reduction may be required in elderly people (increased bioavailability and reduced clearance rate).
The safety and efficacy of pentoxifylline in children poorly understood.
Smoking may reduce the therapeutic efficacy of the drug.