The drug is taken orally once or twice daily. The tablets do not chew and drink plenty of fluids (0.5 to 1 cup), can be taken before meals or between meals. Doses oxandrolone anavar half life are determined by the nature and severity of the infection and the sensitivity of the alleged pathogen.
Patients with normal or moderately decreased kidney function, the recommended dose regimen of the drug:
Sinusitis (inflammation of the sinuses): 500 mg 1 time per day – 10 -14 days.
Exacerbation of chronic bronchitis: 250 mg or 500 mg 1 time per day -7-10 days.
Vnebolnichnaya pneumonia: 500 mg 1-2 times a day – 7-14 days.
Uncomplicated urinary tract infections: 250 mg 1 time per day – 3 days.
Prostatitis: 500 mg – 1 per day – 28 days.
Complicated urinary tract infections, including pyelonephritis: 250 mg 1 time per day – 7-10 days.
Infections of skin and soft tissues: 250 mg 1 time per day or 500 mg 1-2 times a day – 7-14 days.
Septicemia / bacteremia: 250 mg or 500 mg 1-2 times a day – 10-14 days.
Intra-abdominal infections: 250 mg or 500 mg 1 time per day – 7-14 days (in combination with antibacterial drugs acting on the anaerobic flora).
Skin reactions and general hypersensitivity reactions
sometimes itching and redness of the skin. Rare: general reactions of hypersensitivity (anaphylactic and anaphylactoid reaction) with symptoms such as urticaria, bronchoconstriction and possibly – heavy gasps. In very rare cases, – swelling of the skin and mucous membranes ( for example in the areas of the face and throat), sudden drop in blood pressure and shock; increased sensitivity to sunlight and ultraviolet radiation (see “Cautions.”); hypersensitivity pneumonitis; vasculitis. In some cases: severe rash with blistering, such as Stevens-Johnson syndrome, toxic epidermal necrolysis anavar half life and exudative erythema multiforme. General hypersensitivity reactions may sometimes be preceded by lighter skin reactions. The above-mentioned reaction may develop after the first dose in a few minutes or hours after administration.
Action on the gastrointestinal tract and metabolism Common: nausea, diarrhea. Sometimes: loss of appetite, vomiting, abdominal pain, dyspepsia. Rare: bloody diarrhea which in very rare cases, it may be a sign of bowel inflammation and even pseudomembranous colitis (see .. “Cautions”) Very rare: drop in blood sugar levels (hypoglycemia), which has particular importance for patients with diabetes; Possible symptoms of hypoglycemia: “wolf” appetite, nervousness, sweating, trembling. Experience with other quinolones suggests that they are capable of causing an exacerbation of porphyria (a very rare metabolic disease) in patients who are already suffering from the disease. Such an effect is not excluded when using levofloxacin formulation.
Nervous system Occasionally: headache, dizziness, and / or numbness, drowsiness, and sleep disorders. Rare: depression, anxiety, psychotic reactions (eg, hallucinations), discomfort (eg, paresthesias in the hands), tremor, psychotic reactions such as hallucinations and depression, restlessness, seizures, and mental confusion. Very rare: visual and hearing impairment, disturbances of taste and smell sensitivity, reduction of tactile sensitivity.
The action on the cardiovascular system Rare: increased heart rate, decreased blood pressure. Very rare: (shock-like) vascular collapse. In some cases: lengthening interval.
Action on myshiy, tendons and bones Rare: defeat tendons (including tendonitis), joint and muscle pain. Very rare: tendon rupture (eg Achilles tendon); this side effect may occur within 48 hours after the start of treatment and may be bilateral in nature (see “Cautions.”); muscle weakness, which is of particular importance for patients with bulbar syndrome. In some cases: muscle damage (rhabdomyolysis).
Action on the liver and kidney Common: increase in anavar half life liver enzymes (eg, alanine aminotransferase and aspartate aminotransferase). Rare: increased levels of bilirubin and serum creatinine (sign of limitation of the liver or kidney). Very rare: hepatic reactions (eg, inflammation of the liver); deterioration of renal function until the acute renal failure, for example, due to allergic reactions (interstitial nephritis).